Outcome prediction of enteral levodopa/carbidopa infusion in advanced Parkinson's disease
Document identifier: oai:dalea.du.se:1905
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10.1016/j.parkreldis.2006.02.006Keyword: Medical and Health Sciences,
Clinical Medicine,
Medicin och hälsovetenskap,
Klinisk medicin,
Natural Sciences,
Computer and Information Sciences,
Naturvetenskap,
Data- och informationsvetenskap,
Outcome prediction,
Predictive model,
Predictive factor Parkinson,
Continous dopaminergic stimulation,
Improvement measure,
Infusion,
LevodopaPublication year: 2006Relevant Sustainable Development Goals (SDGs):
The SDG label(s) above have been assigned by OSDG.aiAbstract: Two studies comparing intraduodenal infusion of a levodopa/carbidopa gel with oral treatments in advanced PD patients, demonstrated improvement in UPDRS scores and in frequent clinical ratings on a global treatment response scale. Further analysis of data from these studies was performed to find predictive factors related to degree of improvement with infusion. Pearson correlation coefficients between measures of improvement and baseline variables were calculated. Using data from one study, a prediction model was designed and was then evaluated using the other study’s data. Correlations were found indicating that patients with more severe symptoms at baseline were most improved after infusion.
Authors
Jerker Westin
Högskolan Dalarna; Datateknik
Other publications
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Dag Nyholm
Other publications
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Torgny Groth
Other publications
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Mark Dougherty
Högskolan Dalarna; Datateknik
Other publications
>>
Praveen Yerramsetty
Other publications
>>
Sven Pålhagen
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>>
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identifier: oai:dalea.du.se:1905
datestamp: 2021-04-15T13:27:02Z
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recordCreationDate: 2006-03-07
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http://urn.kb.se/resolve?urn=urn:nbn:se:du-1905
10.1016/j.parkreldis.2006.02.006
16731025
titleInfo:
@attributes:
lang: eng
title: Outcome prediction of enteral levodopa/carbidopa infusion in advanced Parkinson's disease
abstract: Two studies comparing intraduodenal infusion of a levodopa/carbidopa gel with oral treatments in advanced PD patients demonstrated improvement in UPDRS scores and in frequent clinical ratings on a global treatment response scale. Further analysis of data from these studies was performed to find predictive factors related to degree of improvement with infusion. Pearson correlation coefficients between measures of improvement and baseline variables were calculated. Using data from one study a prediction model was designed and was then evaluated using the other study’s data. Correlations were found indicating that patients with more severe symptoms at baseline were most improved after infusion.
subject:
@attributes:
lang: eng
authority: uka.se
topic:
Medical and Health Sciences
Clinical Medicine
@attributes:
lang: swe
authority: uka.se
topic:
Medicin och hälsovetenskap
Klinisk medicin
@attributes:
lang: eng
authority: uka.se
topic:
Natural Sciences
Computer and Information Sciences
@attributes:
lang: swe
authority: uka.se
topic:
Naturvetenskap
Data- och informationsvetenskap
@attributes:
lang: eng
topic: outcome prediction
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lang: eng
topic: predictive model
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lang: eng
topic: predictive factor Parkinson
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lang: eng
topic: continous dopaminergic stimulation
@attributes:
lang: eng
topic: improvement measure
@attributes:
lang: eng
topic: infusion
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lang: eng
topic: levodopa
language:
languageTerm: eng
genre:
publication/journal-article
ref
note:
Published
6
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Westin
Jerker
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Högskolan Dalarna
Datateknik
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jwe
0000-0003-0403-338X
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Nyholm
Dag
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Groth
Torgny
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Dougherty
Mark
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Högskolan Dalarna
Datateknik
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Yerramsetty
Praveen
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Pålhagen
Sven
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originInfo:
dateIssued: 2006
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titleInfo:
title: Parkinsonism & Related Disorders
identifier:
1353-8020
1873-5126
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type: volume
number: 12
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type: issue
number: 8
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