Sol–gel synthesis of calcium phosphate-based biomaterials

A review of environmentally benign, simple, and effective synthesis routes

Document identifier:
Access full text here:10.1007/s10971-020-05245-8
Keyword: Natural Sciences, Maskinteknik, Träteknik, Sol–gel synthesis, Composites, Glasses, Calcium phosphates, Calcium hydroxyapatite, Annan maskinteknik, Teknik och teknologier, Chemical Sciences, Other Mechanical Engineering, Mechanical Engineering, Engineering and Technology, Materialkemi, Kemi, Naturvetenskap, Materials Chemistry, Wood Science and Engineering
Publication year: 2020
Relevant Sustainable Development Goals (SDGs):
SDG 9 Industry, innovation and infrastructureSDG 3 Good health and wellbeing
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In this review article the available results about application of sol–gel synthesis method for the preparation of different calcium phosphates and composite materials are summarized. The attention is paid to calcium phosphate-containing compounds which show the biological properties and could be used as potential phosphate bioceramics in medicine. It was demonstrated that the sol–gel synthesis method is a powerful tool for the synthesis of calcium hydroxyapatite and other phosphates, and different calcium phosphate-based composites at mild synthetic conditions resulted in high reproducibility, high phase purity, and desired morphology. Thus, the sol–gel synthesis method enables the researchers to develop biomaterials with superior features in terms of biomedical applications.


Kunio Ishikawa

Department of Biomaterials, Faculty of Dental Science, Kyushu University, Maidashi, Higashi-Ku, Fukuoka, Japan
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Edita Garskaite

Luleå tekniska universitet; Träteknik; Institute of Chemistry, Vilnius University, Vilnius, Lithuania
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Aivaras Kareiva

Institute of Chemistry, Vilnius University, Vilnius, Lithuania
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