Elevated glucose levels in early puerperium, and association with high cortisol levels during parturition

Document identifier: oai:DiVA.org:ltu-7741
Access full text here:10.3109/00365513.2016.1149881
Keyword: Medical and Health Sciences, Health Sciences, Other Health Sciences, Medicin och hälsovetenskap, Hälsovetenskaper, Annan hälsovetenskap, Health Science, Hälsovetenskap
Publication year: 2016
Relevant Sustainable Development Goals (SDGs):
SDG 3 Good health and wellbeing
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Abstract:

Background Gestational diabetes is one of the commonest metabolic problems associated with pregnancy and an accurate diagnosis is critical for the care. Research has shown that pregnant women have high levels of cortisol during the last stage of parturition. As cortisol is a diabetogenic hormone causing increased glucose levels, we wanted to study the association between cortisol and glucose levels during parturition. Materials and methods Glucose and cortisol were analyzed during parturition in 50 females divided according to slow (n = 11) and normal labors (n = 39). Blood samples were analyzed three times during the parturition and four times in the first day after delivery. Glucose levels were also measured once in each trimester. Results In the normal group, the glucose concentration increased from 6.2 (IQR 5.6-8.0) mmol/L in the latency phase to 11.6 (10.0-13.3) mmol/L at aftercare (p < 0.05). After parturition the glucose concentrations decreased gradually. There were significant Spearman rank correlations between glucose and cortisol values. Conclusions The changes associated with birth cause significant elevations of cortisol and glucose around parturition

Authors

Anitha Risberg

Luleå tekniska universitet; Hälsa och rehabilitering
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Mats Sjöquist

Sveriges Lantbruksuniversitet, Swedish Centre for Animal Welfare, Swedish University of Agricultural Sciences, Uppsala
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Kaj Wedenberg

Västerås Hospital
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Anders Larsson

Department of Medical Sciences, Uppsala University
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